Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep168 | Bone and Calcium | ECE2020

Inactivation of diabetoporosity-associated miRNAs in human mesenchymal stem cells

Fößl Ines , Haudum Christoph , Trummer Olivia , Dobnig Harald , Fahrleitner-Pammer Astrid , Kassem Moustapha , Obermayer-Pietsch Barbara , van de Peppel Jeroen

Introduction: Osteoporosis is a disease characterized by the loss of bone density and deficits in bone microarchitecture. “Diabetoporosity” is a new term for osteoporosis in diabetes mellitus type 2 (T2DM) patients, where classical tools for the assessment of bone properties like dual x-ray absorptiometry or bone turnover markers are lacking prognostic accuracy for the determination of bone quality and fracture risk.MicroRNAs (miRNAs) are get...